Research Guides

Department of Chemistry University of Oxford

Professor Andrew S. Weller

Research in the Weller group is based upon synthetic organometallic chemistry and catalysis, and in particular the generation and stabilisation of transition metal complexes with a low coordination number. These complexes often show very interesting, and novel, structures that display C–H, B–H and C–C bonding modes (via agostic or sigma interactions). Not only are we interested in the fundamentals of synthesis, bonding and structure of these complexes, but we also have a focus on their use and development in challenging catalytic bond transformations, such as C–H, B–H and C–C activation. Collaborations with synthetic organic chemists (Professor Michael Willis, Oxford), computational chemists (Professor Stuart Macgregor, Heriot–Watt), experts in the study of mechanism using kinetics (Professor Guy Lloyd–Jones, Edinburgh) and novel analytical techniques (Professor J. S. McIndoe, University of Victoria), and Inorganic Materials Chemists (Professor Ian Manners, Bristol) also lead to a deeper understanding of structures and reactivity and applications of many of the new complexes and catalytic systems discovered. Please follow the link to our Research Group Webpages for more information on the group, its research and our publications.

2018

J. Barwick-Silk, S. Hardy, M. C. Willis and A. S. Weller* Rh(DPEPhos)-Catalyzed Alkyne Hydroacylation using β-Carbonyl Substituted Aldehydes. Mechanistic Insight Leads to Low Catalyst Loadings that Enables Selective Catalysis on Gram-Scale J. Am. Chem. Soc. 2018 in the press.

G. M. Adams, A. L. Colebatch, J. T. Skornia, A. I. McKay, H. C. Johnson, G. C. Lloyd–Jones, S. A. Macgregor, N. A. Beattie, A.S. Weller* The Dehydropolymerization of H3B•NMeH2 to form Polyaminoboranes using [Rh(Xantphos–alkyl)] Catalysts. J. Am. Chem. Soc. 2018140, 1481

A. Grigoropoulos, A. I. McKay, A. P. Katsoulidis, R. P. Davies, A. Haynes, L. Brammer, J. Xiao, A. S. Weller* and M J. Rosseinsky* Encapsulation of Crabtree's catalyst in sulfonated MIL-101(Cr): enhancement of stability and selectivity between competing reaction pathways by the MOF chemical microenvironment Angew. Chem. Int. Ed. 201857, 4532

2017

F. M. Chadwick, A. I. McKay, A. J. Martinez–Martinez, N. H. Rees, T. Krämer, S. A. Macgregor* and A. S. Weller* Solid–State Molecular Organometallic Chemistry. Single–Crystal to Single–Crystal Reactivity and Catalysis with Light Hydrocarbon Substrates. Chem. Sci. 2017, 8, 6014 

T. J. Coxon, M. Fernández, J. Barwick-Silk, A. I. Mckay, L. E. Britton, A. S. Weller and M. C. Willis* Exploiting Carbonyl Groups to Control Intermolecular Rhodium-Catalyzed Alkene and Alkyne Hydroacylation J. Am. Chem. Soc. 2017, 139, 10142

X. Wang, T. N. Hooper, A. Kumar, l. K. Priest, Y. Sheng, T. O. M. Samuels, S. Wang, A. W. Robertson, M. Pacios, H. Bhaskaran, A. S. Weller*, J. H. Warner* Oligomeric Aminoborane Precursors for the Chemical Vapour Deposition Growth of Few-Layer Hexagonal Boron Nitride Cryst. Eng. Commun. 2017, 19, 285 

2016

F. M. Chadwick, T. Krämer, T. Gutmann, N. H. Rees, A. L. Thompson, A. J. Edwards, G. Buntkowsky, S. A. Macgregor,* and A. S. Weller* Selective C-H Activation at a Molecular Rhodium Sigma-Alkane Complex by Solid/Gas Single-Crystal to Single-Crystal H/D Exchange. J. Am. Chem. Soc. 2016, 138, 13369.

A. S. Weller*, F. M. Chadwick and A. I. McKay, Transition Metal Alkane Sigma–Complexes: Synthesis, Characterization and Reactivity, Adv. Organomet. Chem. 2016, 66, 223.

A. Kumar, N. A. Beattie, S. D. Pike, S. A. Macgregor,* A. S. Weller* The Simplest Amino-borane H2B=NH2 Trapped on a Rhodium Dimer Angew. Chem. Int. Ed. 2016, 55, 6551.

F. M. Chadwick, N. H. Rees, A. S. Weller,* T. Krämer, M. Iannuzzi, S. A. Macgregor,* A Rh–pentane sigma–alkane complex. Characterization in the solid–state by experimental and computational techniques Angew. Chem. Int. Ed. 2016, 55, 3677. 

T. N. Hooper, A. S. Weller*, N. A. Beattie and S. A. Macgregor* Dehydrocoupling of Phosphine-Boranes Using the [RhCp*Me(PMe3)(CH2Cl2)][BArF4] Precatalyst: Stoichiometric and Catalytic Studies Chem. Sci. 2016, 7, 2414 

A. Grigoropoulos, G. F. S. Whitehead, N. Perret, A. P. Katsoulidis, F. M. Chadwick, R P. Davies, A. Haynes, L. Brammer, A. S. Weller,* J. Xiao, Matthew J. Rosseinsky* Encapsulation of an organometallic cationic catalyst by direct exchange into an anionic MOF Chem. Sci. 2016, 7, 2037. 

2015

H. C. Johnson* and Andrew S. Weller* P⎼C Activated Bimetallic Rhodium Xantphos Complexes: Formation and Catalytic Dehydrocoupling of Amine–Boranes Angew. Chem. Int. Ed. 2015, 54, 10173.

A. Prades, M. Fernández, S. D. Pike, M.C. Willis* and A. S. Weller* Well-Defined and Robust Rhodium Catalysts for the Hydroacylation of Terminal and Internal Alkenes Angew. Chem. Int. Ed. 2015, 54, 8520 

S. D. Pike, T. Krämer N. H. Rees, S. A. Macgregor,* A. S. Weller* Stoichiometric and Catalytic Solid–Gas Reactivity of Rhodium Bis–Phosphine Complexes. Organometallics 2015, 34, 1487.  Selected by the Editors as the Front Cover

 P. Ren, S. D. Pike, I. Pernik, A. S. Weller* and M.C. Willis Rh–POP Pincer Xantphos Complexes for C–S and C–H Activation. Implications for Carbothiolation Catalysis. Organometallics 2015, 34, 711. 

 S. D. Pike, F. M. Chadwick, N. H. Rees, M. P. Scott, A. S. Weller,* T. Krämer, and S. A. Macgregor* Solid–State Synthesis and Characterization of Sigma−Alkane Complexes, [Rh(L2)(η22–C7H12)][BArF4] (L2 = Bidentate Chelating Phosphine). J. Am. Chem. Soc. 2015, 137, 820 Selected as a JACS Editors’ Spotlight Article 

H. C. Johnson, T. N. Hooper and A. S. Weller The Catalytic Dehydrocoupling of Amine– and Phosphine– Boranes, Top. Organomet. Chem. 2015, 49, 153.