Research Guides

Department of Chemistry University of Oxford

Dr Mohammadali Foroozandeh

Royal Society University Research Fellow

Chemistry Research Laboratory,

12 Mansfield Road,
Office: S1 (2nd floor, room 1)
Telephone: 44 (0) 1865 272 634

Our research revolves around the design and applications of novel methodologies for detection and analysis of magnetic resonance (NMR, EPR, MRI, and in vivo MRS) spectroscopic data, especially drawing on numerical methods, optimisation techniques, and computational learning theory.

In collaboration with researchers from a wide range of disciplines (chemists, biologists, mathematicians, physicists, computer scientists, and spectroscopists) we aim at a holistic approach in magnetic resonance method development. Using a wide range of tools, we design novel ultrahigh-resolution NMR techniques for broadband homodecoupling and RDC measurements, ultra-broadband pulses for NMR and EPR, and develop data processing tools for analysis of MR spectra and images, and we apply these technologies to challenging real problems in chemical research including the study of structures, reactions, and dynamics of small and large molecules.

Moreover, as part of our research objectives in MR method development, we seek a better understanding of mechanisms and phenomena involved, which leads not only to better techniques but also to better ways of designing those techniques.

Joining us

If you are interested in working with us and participating in our trans-disciplinary projects as Part II student, PhD student, PDRA, or academic visitor, please contact us by email.

An 18-month Postdoctoral Research Associate position funded by the Royal Society is available in our group

To apply for this role and for further details, please click on the following link : Job Title - Postdoctoral Research Associate in Magnetic Resonance Method Development - 139459



25. Improved ultra-broadband chirp excitation
Foroozandeh, M.; Nilsson, M.; Morris, G.A.
J. Magn. Reson. 2019, 302, 28-33
DOI: 10.1016/j.jmr.2019.03.007

24. Unexploited Dimension: New Software for Mixture Analysis by 3D Diffusion-Ordered NMR Spectroscopy
Dal Poggetto, G.; CastaƱar, L; Foroozandeh, M.; Kiraly, P; Adams, R.W.; Morris, G.A.; Nilsson, M.
Anal. Chem. 2018, 90 (22), 13695-13701
DOI: 10.1021/acs.analchem.8b04093

23. Suppression of 13C satellites in 1H DOSY spectra
Moutzouri, P.; Kiraly, P.; Foroozandeh, M.; Phillips, A. R.; Coombes, S. R.; Nilsson, M.; Morris, G. A.
J. Magn. Reson 2018, 295, 6-11
DOI: 10.1016/j.jmr.2018.07.011

22. PSYCHE Pure Shift NMR Spectroscopy
Foroozandeh, M.; Morris, G. A.; Nilsson, M.
Chem. Eur. J. 2018, 24, 1-14
DOI: 10.1002/chem.201800524

21. Ultraclean pure shift NMR
Moutzouri, P.; Chen, Y.; Foroozandeh, M.; Kiraly, P.; Phillips, A. R.; Coombes, S. R.; Nilsson, M.; Morris, G. A.
Chem. Commun. 2017, 53, 10188-10191
DOI: 10.1039/C7CC04423B

20. Anatomising Proton NMR Spectra with Pure Shift 2D J-Spectroscopy: A Cautionary Tale
Kiraly, P.; Foroozandeh, M.; Nilsson, M.; Morris, G. A.
Chem. Phys. Lett. 2017, 683, 398-403
DOI: 10.1016/j.cplett.2017.01.031

19. Ultrahigh-Resolution Diffusion-Ordered Spectroscopy
Foroozandeh, M.;Castanar, L.; Martins, L. G.; Sinnaeve, D.; Dal Poggetto, G.; Tormena, C. F.; Adams, R. W.; Morris, G. A.; Nilsson, M.
Angew. Chem. Int. Ed. 2016, 55, 50, 15579-15582
DOI: 10.1002/ange.201609676

18. A General Method for Extracting Individual Coupling Constants from Crowded 1H NMR Spectra
Sinnaeve, D; Foroozandeh, M.; Nilsson, M.; Morris, G. A.
Angew. Chem. Int. Ed. 2016, 55, 1090-1093
DOI: 10.1002/anie.201508691

17. Very broadband diffusion-ordered NMR spectroscopy: 19F DOSY
Power, J. E.; Foroozandeh, M.; Moutzouri, P; Adams, R. W.; Nilsson, M.; Coombes, S. R.; Phillips, A. R.; Morris, G. A.
Chem. Commun. 2016, 52, 6892-6894
DOI: 10.1039/c6cc02917e

16. Increasing the quantitative bandwidth of NMR measurements
Power, J. E.; Foroozandeh, M.; Adams, R. W.; Nilsson, M.; Coombes, S. R.; Phillips, A. R.; Morris, G. A.
Chem. Commun. 2016, 52, 2916-2919
DOI: 10.1039/c5cc10206e

15. Measuring couplings in crowded NMR spectra: pure shift NMR with multiplet analysis
Foroozandeh, M.; Adams, R. W.; Kiraly, P.; Nilsson, M.; Morris, G. A.
Chem. Commun. 2015, 15410-15413
DOI: 10.1039/C5CC06293D

14. Reconstruction of full high-resolution HSQC using signal split in aliased spectra
Foroozandeh, M.; Jeannerat, D.
Magn. Reson. Chem. 2015
DOI: 10.1002/mrc.4283

13. Real-time pure shift 15N HSQC of proteins: a real improvement in resolution and sensitivity
Peter Kiraly, Ralph W. Adams, Liladhar Paudel, Mohammadali Foroozandeh, Juan A. Aguilar, Istvan Timari, Matthew J. Cliff, Mathias Nilsson, Peter Sandor, Gyula Batta, Jonathan P. Waltho, Katalin E. Kover, Gareth A. Morris
J. Boimol. NMR 2015
DOI: 10.1007/s10858-015-9913-z

12. Flaws in foldamers: conformational uniformity and signal decay in achiral helical peptide oligomers
Bryden Le Bailly, Liam Byrne, Vincent Diemer, Mohammadali Foroozandeh, Gareth A Morris and Jonathan Clayden
Chem. Sci. 2015
DOI: 10.1039/C4SC03944K

11. Ultrahigh-Resolution Total Correlation NMR Spectroscopy
Foroozandeh, M., Adams R.W., Nilsson M., Morris G.A.
J. Am. Chem. Soc. 2014
DOI: 10.1021/ja507201t

10. Ultrahigh-Resolution NMR Spectroscopy
Foroozandeh, M., Adams R.W., Meharry N.J., Jeannerat D., Nilsson M., Morris G.A.
Angew. Chem. Int. Ed. 2014, 53, 6990-6992
DOI: 10.1002/anie.201404111

9. Diastereomeric Ratio Determination by High Sensitivity Band-Selective Pure Shift NMR Spectroscopy
R.W. Adams, L. Byrne, P. Kiraly, M. Foroozandeh, L. Paudel, M. Nilsson, J. Clayden, and G.A. Morris
Chem. Commun. 50 (2014), 2512
DOI: 10.1039/C3CC49659G

8. A Toolbox of HSQC Experiments for Small Molecules at High 13C-Enrichment. Artifact-free, Fully 13C-Homodecoupled and JCC-Encoding Pulse Sequences
Foroozandeh, Mohammadali; Giraudeau, Patrick; Jeannerat, Damien
Magn. Reson. Chem. 2013
DOI: 10.1002/mrc.4019

7. Simultaneously Enhancing Spectral Resolution and Sensitivity in Heteronuclear Correlation NMR Spectroscopy
Paudel, Liladhar; Adams, Ralph W.; Kiraly, Peter; Aguilar, Juan A.; Foroozandeh, Mohammadali; Cliff, Matthew J.; Nilsson, Mathias; Sandor, Peter; Waltho, Jonathan P.; Morris, Gareth A.
Angew. Chem. Int. Ed. 2013
DOI: 10.1002/anie.201305709

6. Structure and Dynamic of Three Indole Alkaloids from the Campylospermum Genus (Ochnaceae)
Njock, Gaetan Bayiha Ba; Bartholomeusz, Trixie Ann; Bikobo, Dominique Ngono; Foroozandeh, Mohammadali; Shivapurkar, Rupali; Christen, Philippe; Pegnyemb, Dieudonne Emmanuel; Jeannerat, Damien
Helvetica Chimica Acta 2013 96 7 1298-1304
DOI: 10.1002/hlca.201200327

5. Combination of Homonuclear Decoupling and Spectral Aliasing to Increase the Resolution in the 1H Dimension of 2D NMR Experiments
Cotte, Axelle; Foroozandeh, Mohammadali; Jeannerat, Damien
CHIMIA 2012 66 764-769
DOI: 10.2533/chimia.2012.764

4. NASCA-HMBC, a New NMR Methodology for the Resolution of Severely Overlapping Signals: Application to the Study of Agathisflavone
Njock, Gaetan Bayiha Ba; Bartholomeusz, Trixie Ann; Foroozandeh, Mohammadali; et al.
DOI: 10.1002/pca.1333

3. Broadband 13C-homodecoupled heteronuclear single-quantum correlation nuclear magnetic resonance.
Foroozandeh, Mohammadali; Giraudeau, Patrick; Jeannerat, Damien
ChemPhysChem 2011 12 2409-11
DOI: 10.1002/cphc.201100411

2. Deciphered Chemical Shifts in Aliased Spectra Recorded with two Slightly Different Narrow Windows or Differential Chemical Shift Evolution
Foroozandeh, Mohammadali; Jeannerat, Damien
ChemPhysChem 2010 11 2503-2505
DOI: 10.1002/cphc.201000421

1. Spectral Aliasing: A Super Zoom for 2D-NMR Spectra. Principles and Applications
Njock, GBB ; Pegnyemb, DE; Bartholomeusz, TA; Christen, P; Vitorge, B; Nuzillard, JM; Shivapurkar, R; Foroozandeh, M; Jeannerat, D. CHIMIA 2010 64 235-240
DOI: 10.2533/chimia.2010.235