Research Guides

We are an interdisciplinary research group that focusses on the development and application of new optical methodologies to study structure and dynamics down to nanometer length scales and femtosecond timescales. Our research is motivated by a vigorous back and forth between pushing the boundaries of what we can measure with light and the application of our developments to fundamental questions in chemistry, physics and biology. We are interested in a wide range of phenomena including the origin of life, nanoscale dynamics of proteins and ultra sensitive optical sensing down to individual molecules all the way to the fundamentals of the interaction between light and matter. Please visit our research group pages for more details. 

1. Ortega-Arroyo J, Kukura P Non-fluorescent schemes for single molecule detection, imaging and spectroscopy. Nat. Photonics 2016 10:11-17

2. Mickolajczyk K, Ortega-Arroyo J, Andrecka J, Kukura P, Hancock WO Kinetics of nucleotide-dependent structural transitions in the kinesin-1 hydrolysis cycle. Proc. Natl. Acad. Sci. USA 2015 112:E7186-E7193

3. de Wit G, Danial J, Kukura P*, Wallace MI* Dynamic label-free imaging of lipid nanodomains Proc. Natl. Acad. Sci. USA 2015 112:12299-12303

4. Andrecka J*, Ortega-Arroyo J*, Takagi Y, de Wit G, Fineberg A, MacKinnon L, Young G, Sellers JR, Kukura P Structural dynamics of myosin 5 during processive motion revealed by interferometric scattering microscopy. Elife 2015 4:e05413

5. Musser AJ*, Liebel M*, Schnedermann C, Wende T, Kehoe TB, Rao A, Kukura P. Evidence for conical intersection dynamics mediating ultrafast singlet exciton fission. Nature Physics 2015 11:352–357

6. Liebel M, Schnedermann C, Bassolino G, Taylor G, Watts T, Kukura P Direct observation of the coherent nuclear response after the absorption of a photon. Phys. Rev. Lett. 2014 14:238301

7. Liebel M, Schnedermann C, Kukura P Vibrationally coherent crossing and coupling of electronic states. Phys. Rev. Lett. 2014 14:198302

8. Ortega-Arroyo J, 4. Andrecka J, Spillane K, Takagi Y, Sellers JR, Kukura P Label-free, all-optical detection, imaging and tracking of a single protein. Nano Lett. 2014 14:2065-2070