Telephone: 01865 2 85201
Research Group Website
2010-present Professor of Main Group Chemistry, Fellow in Inorganic Chemistry and Tutor for
Graduates, The Queen’s College.
2007-2010 University Lecturer in Inorganic Chemistry and Fellow of the Queen’s College.
1998-2006 School of Chemistry, Cardiff University. Senior lecturer from 2004.
1997-1998 Post-doctoral associate, Imperial College London (with Prof DMP Mingos FRS).
1996-1997 Fulbright Scholar and post-doctoral associate, Notre Dame, Indiana, USA
(with Prof TP Fehlner).
1996 DPhil, Inorganic Chemistry Laboratory, University of Oxford (with Prof AJ Downs).
Research Interests / Highlights
Main Group and Transition Metal Organometallic Chemistry
The Aldridge group specialises in a range of techniques for the synthesis and manipulation of air-sensitive compounds, and uses a variety of approaches (multinuclear NMR, X-ray crystallography, computational chemistry) to characterize new molecules. Active collaborations exist with Ian Fallis (Cardiff), Cameron Jones (Monash, Australia), E. Jemmis (Bangalore, India), Philip Mountford and John McGrady (both Oxford), the Defence Science and Technology Laboratory (Porton Down) and BP (Hull).
Recent highlighted work on M=B double bonds (left) and chemical sensors (right)
FUNDAMENTAL STUDIES OF NOVEL CHEMICAL BONDS:
Analysis of compounds containing M=B multiple bonds by crystallography (left) and quantum chemistry (right).
Highly electrophilic rhodium and iridium complexes in B-H, C-H and N-H activation chemistry:
ANION AND NEUTRAL MOLECULE SENSORS:
The binding of anions by receptor molecules is an area of enormous recent research interest, which is not only relevant to biological systems, but has widespread applications, for example in catalysis and sensor systems. From the viewpoint of sensor design, key features are selectivity (i.e. the recognition of the target anion over possible contaminants) and signalling (i.e. the triggering of a measurable response on anion binding). A wide variety of chemical strategies have been employed to selectively bind anions, and we have been using group 13 based Lewis acids in this area – with the selectivity for given anions based, for example, on the strength of the donor/acceptor bond formed (e.g. for fluoride, F-) or on the complementary geometry of the binding sites and target anion (e.g. for CN-or [CH3CO2]-)
A key future target in this area, ultimately aimed at improving device sensitivity, is the development of catalytic sensors. The aim is to identify host/guest complexes formed between receptor and target analyte which will catalyze an orthogonal reaction. Our approach utilizes electron transfer chemistry as the basis for catalysis, e.g. of a dye bleaching reaction.
design karl v2018vMay