Publications (>200 publications; those so far since 2011 are shown below; full list available here).
1) Osmium-free direct syn-dihydroxylation of alkenes, Carole J. R. Bataille and Timothy J. Donohoe, Chem. Soc. Rev. 2011, 40, 114-128.
2) Recent Developments in Methodology for the Direct Oxyamination of Olefins, Timothy J. Donohoe, Aida Flores, Cedric K.A. Callens, Adam J. Lacy, Akshat H. Rathi, Chem. Eur. J., 2011, 17, 58-76.
3) Heteroaromatic Synthesis via Olefin Cross-Metathesis: Entry to Polysubstituted Pyridines, Timothy J. Donohoe, José Basutto, Akshat H. Rathi and John F. Bower, Organic Letters, 2011, 13, 1036-1039.
4) Palladium nanoparticle-modified carbon nanotubes for electrochemical hydrogenolysis in ionic liquids, Yao Meng, Leigh Aldous, Ben S. Pilgrim, Timothy J. Donohoe and Richard G. Compton, New Journal of Chemistry, 2011, 35, 1369-1375.
5) Exerting Control over the Acyloin Reaction, Timothy J. Donohoe, Ali Jahanshahi, Michael J. Tucker, Farrah L. Bhatti, IshmaelA. Roslan, Mikhail Kabeshov and Gail Wrigley, Chemical Communications, 2011, 47, 5849-5851.
6) Dehydrogenation of Cyclic-Thioethers Bound to a [Rh(diphosphine)]+ Fragment, Romeao Dallanegra, Ben S. Pilgrim, Adrian B. Chaplin, Timothy J. Donohoe and Andrew S. Weller, Dalton Transactions, 2011, 40, 6626-6628.
7) A short and efficient synthesis of neodysiherbaine A using catalytic oxidative cyclisation, Timothy J. Donohoe, Paul Winship, Matthew R. Tatton and Peter Szeto, Angewandte Chemie, Int. Ed. 2011, 50, 7604-7606.
8) Intramolecular Hydride Addition to Pyridinium Salts: New Routes to Enantiopure Dihydropyridones, Timothy J. Donohoe, Matthew J. Connolly, Akshat H. Rathi and Lesley Walton, Organic Letters, 2011, 13, 2074-2077.
9) The Influence of Exocyclic Stereochemistry on the Tethered Aminohydroxylation Reaction, Timothy J. Donohoe, Adam R. Lacy, Akshat H. Rathi, and Daryl S. Walter, Chemistry: An Aisian Journal, 2011, 6, 3214-3222.
10) Surface plasmon resonance imaging of glycoarrays identifies novel and unnatural carbohydrate-based ligands for potential ricin sensor development, Margherita Fais, Rositsa Karamanska, Sarah Allman, Shirley A. Fairhurst, Paolo Innocenti, Antony J. Fairbanks, Timothy J. Donohoe, Benjamin G. Davis, David A. Russell and Robert A. Field, Chemical Science, 2011, 2, 1952.
11) Tethered aminohydroxylation, Timothy J. Donohoe and Stefanie Mesch, Asymmetric Synthesis – The Essentials II. Edited by Mathias Christmann and Stefan Brase, WILEY-VCH, 2011, in the press.
12) Synthesis of 2,4,6-Trisubstituted Pyridines via an Olefin Cross-Metathesis/Heck-Cyclisation-Elimination Sequence, Timothy J. Donohoe, John F. Bower, David B. Baker,José A. Basutto, Louis K. M. Chan and Peter Gallagher, Chemical Communications, 2011, 47, 10611.
13) Amino acid based reoxidants for aminohydroxylation: application to the construction of amino acid-aminoalcohol conjugates, Timothy J. Donohoe, Cedric K. A. Callens, Aida Flores, Stefanie Mesch, Darren L. Poole and Ishmael A. Roslan, Angewandte Chemie Int Ed., 2011, 50, 10957.
14) Total Synthesis of (±)-Streptonigrin: De-novo Construction of a Pentasubstituted Pyridine using Ring Closing Metathesis, Timothy J. Donohoe, Christopher Jones and Luiz Claudio Barbosa, J. Am. Chem. Soc., 2011, 133, 16418.
15) Improvements in the Tethered Aminohydroxylation Reaction and its Application to Total Synthesis, Timothy J. Donohoe, Cedric K. A. Callens, Adam R. Lacy, Christian Winter, European Journal of Organic Chemistry, 2012, 643-650 (plus cover picture for this issue).
16) Direct Preparation of thiazoles, imidazoles, imidazopyridines and thiazolidines from alkenes, Timothy J. Donohoe, Mikhail Kabeshov, Akshat Rathi and Ian E. D. Smith, Org. Biomol. Chem., 2012, 10, 1093-1101.
17) Olefin Cross-Metathesis for the Synthesis of Heteroaromatic Compounds, Timothy J. Donohoe, John F. Bower and Louis K. M. Chan, Organic and Biomolecular Chemistry, 2012, 10, 1322-1328. Designated as a Hot Article.
18) Hydrogen-Bonding-Mediated Directed Osmium Dihydroxylation, Timothy J. Donohoe,* Carole J. R. Bataille, Paolo Innocenti, Organic Reactions 2012, 76, 1-47. ISBN:978-0-470-63843-9.
19) A green approach to Fenton chemistry: Hydroxylation of salicylic acid in aqueous medium using electrogeneration of Fenton's Reagent. J. Panchompoo, L. Aldous, R. G.Compton, M. Kabeshov, B. Pilgrim, T. J. Donohoe, New. J. Chem. 2012, 36, 1265.
20) Synthesis of substituted isoquinolines utilizing palladium-catalyzed α-arylation of ketones, T. J. Donohoe, B. S. Pilgrim, G. R. Jones, J. A. Bassuto, Proc Natl Acad Sci USA, 2012, 109, 11605-11608.
21) Natural Product Synthesis as a Challenging Test of Newly Developed Methodology, T. J. Donohoe, R. Pullin, Chemical Commun. 2012, 48, 11924-11938.
22) Asymmetric Synthesis of the Fully Elaborated Pyrrolidone Core of Oxazolomycin A, T. J. Donohoe, T. J. C. O'Riordan, M. Peifer, C. R. Jones, T. J. Miles, Organic Lett. 2012, 14, 5460-5463.
23) Partial and complete reduction of pyrroles, furans, thiophenes and their benzo-analogues and of aromatic heterocycles containing more than one heteroatom, Timothy J. Donohoe,* Christopher Jones and Christian Winter, Comprehensive Organic Synthesis II , Ed. G. Molander and P. Knochel, Elsevier, 2013, in the press.
24) Oxidative cyclisation for the synthesis of complex THF-containing natural products, Timothy, J. Donohoe, R. D. C. Pullin, Radoslaw M. Lipinski, Pure & Applied Chem. 2013, 85, 1175-1184.
25) Interplay of cascade oxidative cyclisation and hydride shifts in the synthesis of the ABC spiroketal ring system of pectenotoxin-4, T. J. Donohoe, R. M. Lipinski, Angewandte Chemie, 2013, 52, 2491-2494. Designated as a HOT paper.
26) Osmium-Catalyzed Oxidative Cyclization of Dienes and their Derivatives, Timothy J. Donohoe* and Ben Pilgrim, Journal of Organic Chemistry, 2013, 78, 2149-2167. Work from this paper featured in the cover picture for JOC.
27) Vinyl Weinreb Amides: A Versatile Alternative to Vinyl Ketone Substrates for Heck Arylation, David Baker, Peter Gallagher and Timothy J. Donohoe,* Tetrahedron, 2013, 69, 3690-3697.
28) Lithium-4,4'-Di-tert-butylbiphenylide, Christopher R. Jones and Timothy J. Donohoe, Encyclopedia of Reagents for Organic Synthesis, 2013, in the press.
29) Tethered Aminohydroxylation: Synthesis of the β Amino Acid of Microsclerodermins A and B, Robert Pullin, Akshat Rathi, Ekaterina Melikhova, Christian Winter, Amber Thompson and Timothy J. Donohoe, Organic Letters, 2013, 15, 5492-5495.
30) Modular isoquinoline synthesis using catalytic enolate arylation and in-situ functionalization, Ben Pilgrim, Alice Gatland, Charlie McTernan, Panayiotis Procopiou, Timothy Donohoe, Organic Letters, 2013, 15, 6190-6193.
31) Total Synthesis of the Antitumor Antibiotic (+/-)-Streptonigrin: First and Second Generation Routes for de-novo Pyridine Formation using Ring Closing Metathesis, Timothy Donohoe, Christopher Jones, Anne Kornahrens, Luiz Barbosa, Louise Walport, Matthew Tatton, Michael O'Hagan, Akshat Rathi, David Baker, J. Org. Chem. 2013, 78, 12338-12350. Selected as a Featured Article.
32) Rhodium-Catalyzed Ketone Methylation Using Methanol Under Mild Conditions: Formation of Alpha-Branched Products, Louis K. M. Chan, Darren L. Poole, Di Shen, Mark P. Healy and Timothy J. Donohoe, Angewandte Chemie Int. Ed., 2014, 53, 761-765. Designated as a HOT paper.
33) De novo Synthesis of Multi-Substituted Aryl Amines using Alkene Cross Metathesis, Matthew Tatton, Iain Simpson and Timothy J. Donohoe, Organic Letters, 2014, 16, 1920-1923.
34) Love–Hate ligands for high resolution analysis of strain in ultra-stable protein/small molecule interactions, M. Fairhead, D. Shen, L. K. M. Chan, E. D. Lowe, T. J. Donohoe, M. Howarth, Bioorganic and Medicinal Chemistry, 2014, 22, 5476-5486.
35) New methods for the synthesis of naphthyl amines; application to the synthesis of dihydrosanguinarine, sanguinarine, oxysanguinarine and maclekarpines B and C, Matthew R. Tatton, Iain Simpson, Timothy J. Donohoe, Chemical Communications, 2014, 50, 11314-11316.
36) Short and efficient syntheses of protoberberine alkaloids using palladium catalyzed enolate arylation, Alice E. Gatland, Ben S. Pilgrim, Panayiotis A. Procopiou and Timothy J. Donohoe, Angewandte Chemie Int. Ed., 2014, 53, 14555-14558.
37) Hydrogen borrowing and interrupted hydrogen borrowing reactions of ketones and methanol, catalysed by iridium, Di Shen, Darren L. Poole, Camilla C. Shotton, Anne F. Kornahrens, Mark P. Healy and Timothy J. Donohoe, Angewandte Chemie Int. Ed., 2015, 54, 1642-1645.
38) Palladium-catalyzed alpha-arylation of carbonyls in the de novo synthesis of aromatic heterocycles, Harish K. Potukuchi, Anatol P. Spork and Timothy J. Donohoe, Organic and Biomolecular Chemistry, 2015, 13. 4367-4373.
39) Modular Synthesis of Highly Substituted Pyridines via Enolate α-Alkenylation, Leo Hardegger, Jacqueline Habegger, Timothy J. Donohoe, Organic Letters, 2015, 17, 3222-3225.
40) Application of Catalytic Z-selective Olefin Metathesis in Natural Product Synthesis, Simon Werrel, Johannes Walker, Timothy J. Donohoe, Tetrahedron Letters, 2015, 56, 5261-5268.
41) Aziridine electrophiles in the functionalisation of peptide chains with amine nucleophiles, Anatol P. Spork, Timothy J. Donohoe, Organic and Biomolecular Chemistry, 2015, 13, 8545-8549.
42) Strategic application and transformation of ortho-di-substituted phenyl and cyclopropyl ketones to expand the scope of hydrogen borrowing catalysis, James R. Frost, Choon Boon Cheong, Wasim M. Akhtar, Dimitri F. J. Caputo, Neil G. Stevenson and Timothy J. Donohoe, J. Am. Chem. Soc. 2015, 137, 15664-15667.
43) Palladium-catalysed enolate arylation as a key C-C bond forming reaction for the synthesis of isoquinolines, Ben S. Pilgrim, Alice E. Gatland, Carlos H. A. Estaves, Charlie T. McTernan, Geraint R. Jones, Matthew R. Tatton, Panayiotis A. Procopiou, Timothy J. Donohoe, Organic and Biomolecular Chemistry, 2016, 14, 1065-1090.
44) Catalytic hypervalent iodine promoters allow styrene dimerisation and the formation of tri- and tetrasubstituted cyclobutanes, Ignacio Colomer, Rosimeire Coura Barcelos and Timothy J. Donohoe, Angewandte Chemie Int. Ed., 2016, 55, 4748-4752.
45) Synthesis of aromatic heterocycles using ring-closing metathesis, Harish K. Potukuchi, Ignacio Colomer, Timothy J. Donohoe, in E. F V. Scriven and C. A. Ramsden, editors, Advances in Heterocyclic Chemistry: Heterocyclic Chemistry in the 21st Century: A tribute to Alan Katritzky, Elsevier, 2016, pp 43-65.
46) Dehydromicrosclerodermin B and microsclerodermin J: total synthesis and structural revision, Ekaterina Y. Melikhova, Robert D. C. Pullin, Christian Winter, Timothy J. Donohoe, Angewandte Chemie Int. Ed., 2016, 55, 9753-9757.
47) Hydrogen bonding to hexafluoroisopropanol controls the oxidative strength of hypervalent iodine reagents, Ignacio Colomer, Christopher Batchelor-McAuley, Barbara Odell, Timothy J. Donohoe, Richard Compton, J. Am. Chem. Soc. 2016, 138, 8855-8861.
48) Orthogonally protected 1,2 diols from electron-rich alkenes using metal free olefin syn dihydroxylation, Ignacio Colomer, Rosimeire Coura Barcelos, Kirsten E. Christensen, Timothy J. Donohoe, Organic Letters, 2016, 18, 5880-5883.
49) Iridium-Catalyzed C4-Alkylation of 2,6-Di-tert-butylphenol using Hydrogen Borrowing Catalysis, James R. Frost, Choon Boon Cheong, Timothy J. Donohoe, Synthesis, 2017, 49, 910-916.
50) Diastereoselective synthesis of the 5-hydroxy-pyrrolidinone amino acid of the microsclerodermins and model studies for an end-game strategy for microsclerodermin B, Christian Winter, Robert D. C. Pullin and Timothy J. Donohoe, Tetrahedron Letters, 2017, 58, 602-605.
51) Hydrogen borrowing catalysis with secondary alcohols: a new route for the generation of β-branched carbonyl compounds, Wasim Akhtar, Cheong Choon Boon, James Frost, Kirsten Christensen, Neil Stevenson and Timothy J. Donohoe, J. Am. Chem. Soc. 2017, 139, 2577-2580.
52) Catalytic enolate arylation with 3-bromoindoles allows the formation of beta-carbolines, C. Henrique Estaves, Christopher Hall, Peter Smith, Timothy .J Donohoe, J. Org. Chem. 2017, 82, 4435-4443.
53) Pyruvate enolate arylation and alkylation:OBO ester protected pyruvates as useful reagents in organic synthesis, C. Henrique Estaves, Christopher Hall, Peter Smith, Timothy J. Donohoe, Organic Letters, 2017, 19, 5248-5251.
54) Hexafluoroisopropanol as a highly versatile solvent, Ignacio Colomer, Anna Chamberlain, Maxwell Haughey, Timothy J. Donohoe, Nature Chem Rev. 2017, 1, 0088.
55) Cobalt versus osmium: control of both trans and cis stereoselectivity in construction of the EFG rings of pectenotoxin 4, Ahria Roushanbakhti, Yifan Liu, Paul M. Winship, Michael . Tucker, Wasim M. Akhtar, Daryl S. Walter, Gail Wrigley, Timothy . Donohoe, Angew. Chem. Int. Ed. 2017, 56, 14883-14887.
56) The efficacy of the quertin analogue LY294002 in immortalized cancer cell lines is related to the oxygenic and metabolic status of cells, Xinyue Huang, Michelle Potter, Ben Pilgrom, Ruchuta Ardkhean, Mikail Kabeshov, Timothy Claridge, Matthew Wiseman, Karl J. Morten, Timothy J. Donohoe, Helen E. Townley, Int. J. Cancer Ther. Oncol. 2017, 5, 51X.
57) Asymmetric Total Synthesis of (-)-(3R)-Inthomycin C, Sandra Balcells, Maxwell B. Haughey, Johannes C. L. Walker, Laia Josa-Cullere, Christopher Towers, Timothy J. Donohoe, Organic Letters, 2018, 20, 3583-3586.
58) OBO-protected pyruvates as reagents for the synthesis of functionalized heteroaromatic compounds, C. Henrique Alves Estavez, Maria Koyioni, Kirsten E. Christensen, Peter D. Smith, Timothy J. Donohoe, Organic Letters, 2018, 20, 4048-4051.
59) Stereoselective synthesis of cyclohexanes via an iridium catalysed (5+1) annulation strategy, Wasim M. Akhtar, Roly J. Armstrong, James R. Frost, N. G. Stevenson, Timothy J. Donohoe, J. Am. Chem. Soc. 2018, 140, 11916-11920.
60) The reductive C3 functionalization of pyridinium and quinolinium salts through iridium catalysed interrupted transfer hydrogenation, Alex Grozavu, Hamish B. Hepburn, Philip J. Smith, Harish K. Potukuchi, Peter J. Lindsay-Scott, Timothy, J. Donohoe, Nature Chemistry, 2019, 11, 242-247.
61) Synthesis of Lamellarin alkaloids using orthoester masked alpha keto acids, Harry J. Shirley, Maria Koyioni, Filip Muncan, Timothy J. Donohoe, Chem. Sci. 2019, 10, 4434-4338.
62) HFIP solvent enables alcohols to act as alkylating agents in stereoselective heterocyclisation, Yuxiang Zhu, Ignacio Colomer, Timothy J. Donohoe, J. Am. Chem. Soc. 2019, 141, 6489-6493.
63) Rhodium-catalysed vinyl 1,4-conjugate addition coupled with Sharpless asymmetric dihydroxylation in the synthesis of the CDE ring fragment of pectenotoxin 4, Melodie Richardson, Darren Poole, Christopher Tame, Timothy J. Donohoe, Chem. Sci. 2019, 10, 6336-6340.
64) Catalytic asymmetric synthesis of cyclohexanes by hydrogen borrowing annulations, Roly J. Armstrong, Wasim M. Akhtar, Tom A. Young, Fernanda Duartes, Timothy. J. Donohoe, Angewandte Chemie Int Ed. 2019, 58, 12558-12562. Designated as a HOT paper.
65) Hypervalent iodine initiated intramolecular alkene dimerization: a stereodivergent entry to cyclobutanes, Yuxiang Zhu, Ignacio Colomer and Timothy J. Donohoe, Chemical Communications, 2019, 55, 10316-10319.
66) Photochemical alkene isomerisation for the synthesis of polysubstituted furans and pyrroles under neutral conditions, Johannes C. L. Walker, Simon Werrel and Timothy J. Donohoe, Chemistry: A European Journal, 2019, 25, 13114-13118.
67) 1-(4-Methyl-2,6,7-trioxabicyclo[2.2.2]oct-1-yl)-ethane, Christopher Hall and Timothy J. Donohoe, Encyclopedia of Reagents for Organic Synthesis, 2019, ISBN 9780470842898.
68) Transition metal free reductive hydroxymethylation of isoquinolines, Benjamin M. Reeves, Hamish B. Hepburn, Alex Grozavu, Peter J. Lindsay-Scott, Timothy J. Donohoe, Angewandte Chemie Int Ed. 2019, 58, 15697-15701.
69) Stereoselective synthesis of alicyclic ketones: a hydrogen borrowing approach, Roly J. Armstrong, Wasim M. Akhtar, James R. Frost, Kirsten E. Christensen, Neil G. Stevenson, Timothy J. Donohoe, Tetrahedron, 2019, 75, 130680. Steve Davies honor issue.
70) The reductive hydroxymethylation of 4-heteroarylpyridines, Hamish B. Hepburn, Timothy J. Donohoe, Chemistry: A European Journal, 2020, 26, 1963-1967.
71) Chemo- and regioselective synthesis of acyl cyclohexenes by a tandem acceptorless dehydrogenation [1,5]-hydride shift cascade, Lewis B. Smith, Roly J. Armstrong, Timothy J. Donohoe, J. Am. Chem. Soc. 2020, 142, 2514-2523.
72) A hydrogen borrowing annulation strategy for the stereocontrolled synthesis of saturated aza-heterocycles, Anna E. R. Chamberlain, Kieran J. Paterson, Roly J. Armstrong, Heather C. Twin, Timothy J. Donohoe, Chemical Communications, 2020, 56, 3563-3566,
73) Enantioconvergent alkylation of ketones with racemic secondary alcohols via hydrogen borrowing catalysis, Daniella M. J. Cheang, Roly J. Armstrong, Wasim M. Akhtar, Timothy J Donohoe, Chemical Communications, 2020, 56, 3543-3546.
74) Control of absolute stereochemistry in transition metal catalysed hydrogen borrowing reactions, Timothy Kwok, Oskar Hoff, Roly J. Armstrong, Timothy J. Donohoe, Chemistry: A European Journal, 2020, in the press, https://doi.org/10.1002/chem.202001253
75) A vinyl cyclopropane ring expansion and iridium catalysed hydrogen borrowing cascade, Simon Wubbolt, Choon Boon Cheong, James Frost, Kirsten Christensen, Timothy J, Donohoe, Angewandte Chemie. Int. Ed. 2020, 132, 11435-11440. Designated as a HOT paper; highlighted in Synfacts.
76) A Heck reaction/photochemical alkene isomerisation sequence to prepare functionalised quinolines, Alex Kelly, Jack B. Hoffman, Oskar Hoff, Johannes C. L. Walker, Simon Werrel, Timothy J. Donohoe, Tetrahedron, 2020, Richard Taylor honor issue, in the press.
77) Rhodium catalysed C3/5 methylation of pyridines using temporary dearomatisation, Alexandru Grozavu, Hamish B. Hepburn, Elliot P. Bailey, Peter J. Lindsay-Scott, Timothy J. Donohoe, Chemical Science, 2020, 11, in the press.